Activating Compound | Comment | Organism | Structure |
---|---|---|---|
R5020 | stimulates conversion of estradiol to estrone in T47D cells in culture | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-431 cell | - |
Homo sapiens | - |
breast cell line | breast cells, activity is far greater in epithelial cells than in fibroblasts | Homo sapiens | - |
CAOV-3 cell | - |
Homo sapiens | - |
MCF-7 cell | - |
Homo sapiens | - |
MDA-MB-231 cell | - |
Homo sapiens | - |
ovarian cancer cell | - |
Homo sapiens | - |
OVCAR-3 cell | - |
Homo sapiens | - |
T47D cell | - |
Homo sapiens | - |
T47D cell | T47D breast cancer cell line | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
estradiol-17beta + NAD+ | - |
Homo sapiens | estrone + NADH | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | cofactor | Homo sapiens |